Antimalarials in a New Light: The Science Behind Chloroquine's Promise for Lupus, Rheumatoid Arthritis, and Beyond
Chloroquine and its derivative hydroxychloroquine have quietly become cornerstones of autoimmune disease management in the United States, even as their origins lie in tropical medicine. This article examines the pharmacological foundations, emerging clinical trial data, and practical considerations for patients and providers navigating these therapies outside their original indication.